I don't shoot in any competitions, I use an inline, and none of my hunting shots are over 100 yards. There's also not a lot of gun shops nearby that carry real muzzleloading supplies, so Walmart is my main source. I'm sure there is definitely some sort of accuracy difference with loose powder, but for my uses, the pellets work just fine. I won't argue with the fact that loose powder is definitely capable of getting better accuracy.
I can hit an old 4x4 pan out to about 200 yards, past that, and I'm not even going to attempt the shot. Three 777 pellets will consistently do what I need them to do.
I also shoot with quite a bit of loose powder, it's just easier to carry pellets while hunting than powder, for me. They are more or less waterproof (in the tubes that I carry them in) and don't require me to have to focus on pouring loose powder down a barrel, or a few drops of water. I can load simply by pouring the entire tube into the barrel. It's not traditional, but it works well for me.
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That being said, when I hunt with my shotgun, I only use loose powder.